Association between knee osteoarthritis and metabolic syndrome: a systematic review

Authors

DOI:

https://doi.org/10.5020/18061230.2019.8448

Keywords:

Osteoarthritis, Metabolic Syndrome, Obesity, Hypertension

Abstract

Objective: To identify possible associations between knee osteoarthritis (KO) and metabolic syndrome (MS). Methods: A systematic review was carried out between 2012 and 2017 on the Virtual Health Library (VHL), SciELO, Cochrane and Embase databases to search for publications in Portuguese and/or English using the descriptors “osteoarthritis” and “metabolic syndrome” in both languages. Methodological quality was assessed using the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) Statement. Seven articles with high methodological quality were selected. Results: The data point to the association between symptomatic KO and systemic arterial hypertension, dyslipidemia and number of accumulated factors, with increased severity and progression of symptoms in women. However, the association between the pre-inflammatory stage of MS and KO has not yet been fully clarified. Conclusion: The findings suggest that a better understanding of the actions of the metabolic pathways involved in KO could open a new avenue for the treatment of these patients.

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Author Biographies

Maura Fernandes Franco, Universidade Estadual de Campinas

Fisioterapeuta - Mestrado em Gerontologia pelo Programa de Pós-Graduação da Faculdade de Ciencias Médicas da Universidade Estadual de Campinas

Daniel Vicentini De Oliveira, Faculdade Metropolitana de Maringá (FAMMA) Unicesumar Universidade Estadual de Campinas (UNICAMP)

FAMMA e Unicesumar - Departamento de Fisioterapia e Educação Fisica UNICAMP - Programa de Pós-Graduação em Gerontologia

Arlete Maria Valente Coimbra, Universidade Estadual de Campinas

Departamento de Reumatologia e Saúde da Família - UNICAMP Programa de Pós-Graduação em Gerontologia UNICAMP

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Published

2019-04-01

How to Cite

Franco, M. F., De Oliveira, D. V., & Coimbra, A. M. V. (2019). Association between knee osteoarthritis and metabolic syndrome: a systematic review. Brazilian Journal in Health Promotion, 32. https://doi.org/10.5020/18061230.2019.8448

Issue

Vol. 32 (2019)

Section

Articles for review

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