Main human papillomavirus genotypes in riparian women from the brazilian Amazon
DOI:
https://doi.org/10.5020/18061230.2016.p68Keywords:
Papillomaviridae, Genotype, Prevalence, Epidemiology.Abstract
Objective: To assess the distribution of the main oncogenic human papillomavirus (HPV) genotypes in women from riparian and fishing areas in different geographical regions of the Brazilian Amazon. Methods: Cross-sectional study conducted from 2013 to 2014. Participants were 516 riparian and fishing women over 13 years old enrolled in the Programa de Prevenção do Câncer de Colo Uterino – PCCUP (Cervical Cancer Prevention Program) and submitted to the collection of cervicovaginal material for the Pap test, carried out in loco by a doctor member of the research team, DNA/HPV research and genotyping by Polymerase Chain Reaction (PCR), carried out in the Laboratório de Imunopatologia of the Universidade Federal do Pará (Immunopathology Laboratory of the Federal University of Pará) by researchers of the same team. Additionally, information on age and the type of service were also collected by the researchers. All data were analyzed using the Biostat Program 5.0, considering a significant difference when p <0.05. Results: The mean age of women in the communities A and B were respectively 40 and 39 years, while in communities C, D and E the mean age was 37 years. The prevalence of HPV infection ranged 7.6 to 29.2%. Among the studied oncogenic types, HPV52 (n=5; 5.15%), HPV35 (n=4; 4.12%) and HPV58 (n=3; 3.09%) were the most frequent. The main oncogenic types found are concentrated in the regions of Itaituba (communities A, B) and Bragança (community E). Conclusion: All the studied regions presented a high percentageof infection whose HPV type was not identified among the tested individuals, especially communities C and D, with 100% of cases.Downloads
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