Nonalcoholic hepatic steatosis: association with metabolic syndrome and cardiovascular risk factors in obese adolescents

Authors

  • Wener Barbosa Resende
  • Carlos Eduardo Caetano
  • Anamaria Caixeta Nogueira
  • Sandra Xavier
  • Rafael Dias Costa e Silva
  • João Elias Nunes
  • Heitor Dos Santos
  • Nadia Carla Cheik

DOI:

https://doi.org/10.5020/2421

Keywords:

Adolescents, Obesity, Fatty Liver, Metabolic Syndrome X, Cardiovascular Diseases.

Abstract

Objective: To evaluate the association between nonalcoholic hepatic steatosis (NAHS), metabolic syndrome (MS) and cardiovascular risk factors (CRF) in obese adolescents. Methods: Cross-sectional observational study with a quantitative approach, carried out from June to August 2011. The volunteers were randomly selected and referred to clinical evaluation in the endocrinology and cardiology units at the clinics hospital of the Federal University of Uberlândia, being included 34 adolescents of 14-19 years above the 95th percentile of the growth curve. NAHS was assessed by ultrasonography. The MS and CRF were diagnosed by the International Diabetes Federation criteria. Results: The sample consisted of 14 male and 20 female patients aged 16.8 ± 1.6 and body mass index (BMI) of 35.7 ± 3.9. The occurrence of NAHS and MS was 76.5% and 50%, respectively. Males had a higher incidence of NAHS (78.6%), SM (64.3%) and association of NAHS with MS (50%). Regarding the CRF, 100% (n=34), 61.8% (n=21) and 52.9% (n=18) of the adolescents had elevated values of waist circumference (WC), low-density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP), respectively, and 52.9% (n=18) showed low levels of high-density lipoprotein cholesterol (HDL-C). There were correlations between MS and triglycerides; systolic and diastolic blood pressure and HDL-C; and between NAHS and BMI and WC. Conclusion: A high occurrence of NAHS, SM and CRF was observed in obese adolescents. A strong correlation was observed between MS and NAHS, and between FRC and NAHS and SM. doi:10.5020/18061230.2014.p131

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Published

2014-10-09

How to Cite

Resende, W. B., Caetano, C. E., Nogueira, A. C., Xavier, S., Costa e Silva, R. D., Nunes, J. E., Dos Santos, H., & Cheik, N. C. (2014). Nonalcoholic hepatic steatosis: association with metabolic syndrome and cardiovascular risk factors in obese adolescents. Brazilian Journal in Health Promotion, 27(1), 131–139. https://doi.org/10.5020/2421

Issue

Vol. 27 No. 1 (2014)

Section

Original Articles

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